Group

Pontus Nordenfelt

Principal Investigator
Associate Professor and Senior Lecturer
Ph.D. Cell biology and Microbiology/ Immunology
M. Sc. Chemical Engineering

Bio: Pontus Nordenfelt started in Chemical Engineering (M.S.Eng) at LTH in Lund, Sweden. He finished his Ph.D. in 2010 in Cell Biology and Microbiology at Lund University (with Hans Tapper as supervisor) and the University of Toronto (Sergio Grinstein, co-supervisor), focusing on phagocytosis of bacteria. The first postdoc was within Infection Medicine in Lund (Lars Björck and Johan Malmström) with studies on pathogen antibody interaction. This was followed by a longer postdoc in Immunology at Harvard Medical School (Timothy Springer), partly as a Fellow at the Image and Data Analysis Core facility and at MBL Woods Hole during the summers. The second postdoc was focused on integrin biology. With grants from the Swedish Research Council and the Knut and Alice Wallenberg Foundations, he started his group in 2017 as an Assistant Professor at the Faculty of Medicine at Lund University. Pontus Nordenfelt is committed to a quantitative understanding of immunology, cell biology, and microbiology, with a strong interest in antibody function, infection processes, and cell migration. Technologies and molecules of interest include but are not limited to quantitative microscopy, live imaging, single-cell studies, antibodies, complement, and integrins.

Interests: Antibodies, Integrins, Phagocytosis, Cell migration, Host-pathogen interactions, Microscopy, Image analysis

“I believe in finding a scientific question that truly intrigues me, and then push whatever technology is needed to address the question adequately.” 
Member of Sweden’s Young Academy www.sverigesungaakademi.se

Martin Sundwall

Lab manager
M.Sc. Molecular Biology

Projects: integrin biosensors, complement-mediated phagocytosis, bacterial adhesion, antibody generation and characterization

“My primary task in the Nordenfelt lab is to make sure that our everyday work runs smoothly. My area of research includes molecular biology, where the focus lies on cloning and genomic editing of bacteria and eukaryotic cells.  I´m a part time PhD student where my projects focuses in the adherence properties  of Streptococcus pyogenes and my current main focus is on antibody discovery, production and characterization “

Berit Olofsson

Associate Researcher
Ph.D. Biomedicine
M.Sc. Biotechnology

Projects: epIgG

“EpIgG is a collaboration between five research groups with the aim of studying the involvement of immunoglobulins in infectious diseases. My position is shared between these five groups. In the Nordenfelt lab I am responsible for the production, purification and characterization of immunoglobulins with the help of adherent as well as suspension cells. The antibodies are then used in functional assays, physiological models and other downstream applications within epIgG .”

Oscar André

Post-Doc
Ph.D Biomedicine
M.Sc. Biomedicine

Projects: systems microscopy of host-pathogen interactions, image analysis 

“In my work, I primarily develop new imaging strategies and analysis pipelines for data-driven microscopy. Currently studying single-cell interactions between bacterial pathogens and host cells, as well as cancer cell migration on 2D surfaces.”

Johannes Kumra Ahnlide

PhD Student
M. Sc. Eng

Projects: Population-wide single-cell image analysis for prediction of cell behavior, Software development for analysis of high dimensional data

“My research revolves around predicting how properties of cells and cell populations evolve over time as well as developing software to extract these properties from e.g. microscopy images. I’m passionate about programming languages and approaches to abstraction in software. I use Julia, Elixir and Elm for developing open source as well as internal software.”

Arman Izadi

PhD Student
M.D. student

Projects: Role of IgG subclasses in mediating immune functions against S.pyogenes, role of IgG3 and the influence of constant domains in anti-Sars-CoV-2 antibodies

“I´m interested in how complex interactions on protein-level leads to homeostasis but also diseases which I see in the hospital. Currently my research focuses on antibodies- a field which Will dominate future medicine. As a future MD I strongly believe in cross-profession collaboration between preclinical and clinical researchers to advance the field to higher boundaries. My aspiration is to be a link in that important collaboration as a clinical MD but with a PhD in antibody research.”